关于fmri统计推断的一些讨论
Maillist里面关于FWE和FDR的讨论很有趣,其中一封信给了我很多启示。 Dear All, Many mails concerning the FWE and FDR have been posted last days. More generally, I think that the problem with any statistical test of hypothesis is that we give a result which is dependent of the chosen threshold ( Dan Kimberg says " I don't really know much about the historical basis for the gold standard of FWER=0.05, but it's certainly in part cultural (how the standard is imposed varies across sub-fields even within a discipline).") I remember (in field of molecular biology) the example of a well-reputed scientist which definitively rejected a result associated with a p=0.052 and accepted without any doubt a result associated with a p=0.047! I think the point is that the statistical test is only ONE indication (among many others) which has to be taken in the general context of the result. The result has to be related to the physiological and data context. In the physiological context, is the result in a