Nature和Science上的fMRI/PET文章
虽然短期内没有发Nature或Science的可能，但还是不妨仔细研究一下发表在上面的fMRI/PET论文。这样既有利于回顾历史上的重要研究，也能看出一些脑成像研究的发展趋势。
文章主要是我手动从Pubmed搜集的所有发表在Nature和Science上发表的文章。借助云端文献管理软件Mendeley，我分别建立了两个小组来分享发表在Nature和Science上的脑成像文章。文章主要以fMRI和PET为主，也有少量的TMS研究。
这么多文章，一篇一篇看过去也是很有趣的。不过把这些文章整理一下，也可以找到一些有趣的趋势。比如，下图就是我统计的各年发表在Nature和Science上文章的数量。
从中可以看出，Nature中fMRI/PET文章发表的高峰在2000年左右，Science的高峰在2008年左右。而在近年，两个期刊发表的文章数量都有下降趋势。这应该不是fMRI文章发表数量降低导致。因为在Pubmed搜索"functional magnetic resonance imaging"，可以看出相关fMRI文章的数量是一直上升的。可能是近年来有重大突破的文章越来越少了吧。
最后是根据Google Scholar引用数据统计出Nature和Science分别引用最高的10篇fMRI/PET文章 (序号后的数字表示引用数)：
Nature
1. 2233
Petersen SE, Fox PT, Posner MI, Mintun M, Raichle ME, 1988. Positron emission tomographic studies of the cortical anatomy of single-word processing. Nature 331(6157):585-9.
2. 2179
Drevets WC, Price JL, Simpson JR Jr, Todd RD, Reich T, Vannier M, Raichle ME, 1997. Subgenual prefrontal cortex abnormalities in mood disorders. Nature 386(6627):824-7.
3. 1604
Cohen JD, Perlstein WM, Braver TS, Nystrom LE, Noll DC, Jonides J, Smith EE, 1997. Temporal dynamics of brain activation during a working memory task. Nature 386(6625):604-8.
4. 1601
Epstein R, Kanwisher N, 1998. A cortical representation of the local visual environment. Nature 392(6676):598-601.
5. 1447
Botvinick M, Nystrom LE, Fissell K, Carter CS, Cohen JD, 1999. Conflict monitoring versus selection-for-action in anterior cingulate cortex. Nature 402(6758):179-81.
6. 1426
Martin A, Wiggs CL, Ungerleider LG, Haxby JV, 1996. Neural correlates of category-specific knowledge. Nature 379(6566):649-52.
7. 1392
Damasio H, Grabowski TJ, Tranel D, Hichwa RD, Damasio AR, 1996. A neural basis for lexical retrieval. Nature 380(6574):499-505.
8. 1386
Karni A, Meyer G, Jezzard P, Adams MM, Turner R, Ungerleider LG, 1995. Functional MRI evidence for adult motor cortex plasticity during motor skill learning. Nature 377(6545):155-8.
9. 1319
Shaywitz BA, Shaywitz SE, Pugh KR, Constable RT, Skudlarski P, Fulbright RK, Bronen RA, Fletcher JM, Shankweiler DP, Katz L, et al., 1995. Sex differences in the functional organization of the brain for language. Nature 373(6515):607-9.
10. 1264
Phillips ML, Young AW, Senior C, Brammer M, Andrew C, Calder AJ, Bullmore ET, Perrett DI, Rowland D, Williams SC, Gray JA, David AS, 1997. A specific neural substrate for perceiving facial expressions of disgust. Nature 389(6650):495-8.
Science
1. 2493
Carter CS, Braver TS, Barch DM, Botvinick MM, Noll D, Cohen JD, 1998. Anterior Cingulate Cortex, Error Detection, and the Online Monitoring of Performance. Science 280(5364), 747-749.
2. 2350
MacDonald, III, A.W., Cohen, J.D., Stenger, V.A., Carter, C.S.,2000. Dissociating the Role of the Dorsolateral Prefrontal and Anterior Cingulate Cortex in Cognitive Control. Science 288(5472), 1835-1838.
3. 2246
Singer T, Seymour B, O'Doherty J, Kaube H, Dolan RJ, Frith CD, 2004. Empathy for pain involves the affective but not sensory components of pain. Science 303(5661):1157-62.
4. 2239
Iacoboni, M., Woods, R.P., Brass, M., Bekkering, H., Mazziotta, J.C., Rizzolatti, G., 1999. Cortical Mechanisms of Human Imitation. Science 286(5449), 2526-2528.
5. 2132
Greene, J.D., Sommerville, R.B., Nystrom, L.E., Darley, J.M., Cohen, J.D., 2001. An fMRI Investigation of Emotional Engagement in Moral Judgment. Science 293(5537), 2105-2108.
6. 1918
Eisenberger NI, Lieberman MD, Williams KD, 2003. Does rejection hurt? An FMRI study of social exclusion. Science 302(5643):290-2.
7. 1914
Rainville P, Duncan GH, Price DD, Carrier B, Bushnell MC, 1997. Pain affect encoded in human anterior cingulate but not somatosensory cortex. Science 277(5328):968-71.
8. 1908
Sanfey AG, Rilling JK, Aronson JA, Nystrom LE, Cohen JD, 2003. The neural basis of economic decision-making in the ultimatum game. Science 300(5626):1755-8.
9. 1901
Haxby, J.V., Gobbini, M.I., Furey, M.L., Ishai, A., Schouten, J.L., Pietrini, P., 2001. Distributed and Overlapping Representations of Faces and Objects in Ventral Temporal Cortex. Science 293(5539), 2425 - 2430.
10. 1801
Sereno, M.I., Dale, A.M., Reppas, J.B., Kwong, K.K., Belliveau, J.W., Brady, T.J., Rosen, B.R., Tootell, R.B., 1995. Borders of multiple visual areas in humans revealed by functional magnetic resonance imaging. Science 268(5212), 889-893.
文章主要是我手动从Pubmed搜集的所有发表在Nature和Science上发表的文章。借助云端文献管理软件Mendeley，我分别建立了两个小组来分享发表在Nature和Science上的脑成像文章。文章主要以fMRI和PET为主，也有少量的TMS研究。
这么多文章，一篇一篇看过去也是很有趣的。不过把这些文章整理一下，也可以找到一些有趣的趋势。比如，下图就是我统计的各年发表在Nature和Science上文章的数量。
从中可以看出，Nature中fMRI/PET文章发表的高峰在2000年左右，Science的高峰在2008年左右。而在近年，两个期刊发表的文章数量都有下降趋势。这应该不是fMRI文章发表数量降低导致。因为在Pubmed搜索"functional magnetic resonance imaging"，可以看出相关fMRI文章的数量是一直上升的。可能是近年来有重大突破的文章越来越少了吧。
最后是根据Google Scholar引用数据统计出Nature和Science分别引用最高的10篇fMRI/PET文章 (序号后的数字表示引用数)：
Nature
1. 2233
Petersen SE, Fox PT, Posner MI, Mintun M, Raichle ME, 1988. Positron emission tomographic studies of the cortical anatomy of single-word processing. Nature 331(6157):585-9.
2. 2179
Drevets WC, Price JL, Simpson JR Jr, Todd RD, Reich T, Vannier M, Raichle ME, 1997. Subgenual prefrontal cortex abnormalities in mood disorders. Nature 386(6627):824-7.
3. 1604
Cohen JD, Perlstein WM, Braver TS, Nystrom LE, Noll DC, Jonides J, Smith EE, 1997. Temporal dynamics of brain activation during a working memory task. Nature 386(6625):604-8.
4. 1601
Epstein R, Kanwisher N, 1998. A cortical representation of the local visual environment. Nature 392(6676):598-601.
5. 1447
Botvinick M, Nystrom LE, Fissell K, Carter CS, Cohen JD, 1999. Conflict monitoring versus selection-for-action in anterior cingulate cortex. Nature 402(6758):179-81.
6. 1426
Martin A, Wiggs CL, Ungerleider LG, Haxby JV, 1996. Neural correlates of category-specific knowledge. Nature 379(6566):649-52.
7. 1392
Damasio H, Grabowski TJ, Tranel D, Hichwa RD, Damasio AR, 1996. A neural basis for lexical retrieval. Nature 380(6574):499-505.
8. 1386
Karni A, Meyer G, Jezzard P, Adams MM, Turner R, Ungerleider LG, 1995. Functional MRI evidence for adult motor cortex plasticity during motor skill learning. Nature 377(6545):155-8.
9. 1319
Shaywitz BA, Shaywitz SE, Pugh KR, Constable RT, Skudlarski P, Fulbright RK, Bronen RA, Fletcher JM, Shankweiler DP, Katz L, et al., 1995. Sex differences in the functional organization of the brain for language. Nature 373(6515):607-9.
10. 1264
Phillips ML, Young AW, Senior C, Brammer M, Andrew C, Calder AJ, Bullmore ET, Perrett DI, Rowland D, Williams SC, Gray JA, David AS, 1997. A specific neural substrate for perceiving facial expressions of disgust. Nature 389(6650):495-8.
Science
1. 2493
Carter CS, Braver TS, Barch DM, Botvinick MM, Noll D, Cohen JD, 1998. Anterior Cingulate Cortex, Error Detection, and the Online Monitoring of Performance. Science 280(5364), 747-749.
2. 2350
MacDonald, III, A.W., Cohen, J.D., Stenger, V.A., Carter, C.S.,2000. Dissociating the Role of the Dorsolateral Prefrontal and Anterior Cingulate Cortex in Cognitive Control. Science 288(5472), 1835-1838.
3. 2246
Singer T, Seymour B, O'Doherty J, Kaube H, Dolan RJ, Frith CD, 2004. Empathy for pain involves the affective but not sensory components of pain. Science 303(5661):1157-62.
4. 2239
Iacoboni, M., Woods, R.P., Brass, M., Bekkering, H., Mazziotta, J.C., Rizzolatti, G., 1999. Cortical Mechanisms of Human Imitation. Science 286(5449), 2526-2528.
5. 2132
Greene, J.D., Sommerville, R.B., Nystrom, L.E., Darley, J.M., Cohen, J.D., 2001. An fMRI Investigation of Emotional Engagement in Moral Judgment. Science 293(5537), 2105-2108.
6. 1918
Eisenberger NI, Lieberman MD, Williams KD, 2003. Does rejection hurt? An FMRI study of social exclusion. Science 302(5643):290-2.
7. 1914
Rainville P, Duncan GH, Price DD, Carrier B, Bushnell MC, 1997. Pain affect encoded in human anterior cingulate but not somatosensory cortex. Science 277(5328):968-71.
8. 1908
Sanfey AG, Rilling JK, Aronson JA, Nystrom LE, Cohen JD, 2003. The neural basis of economic decision-making in the ultimatum game. Science 300(5626):1755-8.
9. 1901
Haxby, J.V., Gobbini, M.I., Furey, M.L., Ishai, A., Schouten, J.L., Pietrini, P., 2001. Distributed and Overlapping Representations of Faces and Objects in Ventral Temporal Cortex. Science 293(5539), 2425 - 2430.
10. 1801
Sereno, M.I., Dale, A.M., Reppas, J.B., Kwong, K.K., Belliveau, J.W., Brady, T.J., Rosen, B.R., Tootell, R.B., 1995. Borders of multiple visual areas in humans revealed by functional magnetic resonance imaging. Science 268(5212), 889-893.
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